ARG52539

anti-CD276 / B7-H3 antibody [SP206]

anti-CD276 / B7-H3 antibody [SP206] for IHC-Formalin-fixed paraffin-embedded sections,Western blot,Flow cytometry and Human

Cancer antibody; Developmental Biology antibody; Immune System antibody

Overview

Product Description Rabbit Monoclonal antibody [SP206] recognizes CD276 / B7-H3
Tested Reactivity Hu
Tested Application FACS, IHC-P, WB
Host Rabbit
Clonality Monoclonal
Clone SP206
Isotype IgG
Target Name CD276 / B7-H3
Antigen Species Human
Immunogen Synthetic peptide derived from human B7-H3 protein.
Conjugation Un-conjugated
Alternate Names B7-H3; B7 homolog 3; B7H3; 4Ig-B7-H3; B7RP-2; Costimulatory molecule; CD antigen CD276; CD276 antigen

Application Instructions

Application Suggestion
Tested Application Dilution
FACSAssay-Dependent
IHC-P1:100
WB1:400
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Tonsil, 293T Cell Lysate

Properties

Form Liquid
Purification Purified by protein A/G
Buffer PBS (pH 7.6), 1% BSA and < 0.1% Sodium azide
Preservative < 0.1% Sodium azide
Stabilizer 1% BSA
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 80381 Human CD276

Swiss-port # Q5ZPR3 Human CD276 antigen

Background CD276 (also known as B7-H3) is a membrane protein that participates in the regulation of T cell-mediated immune response. It is expressed widely in dendritic cells, some epithelial cells, trophoblast cells, Hofbauer cells of the placenta, activated B and T cells, NK cells, and monocytes. CD276 is also expressed by some solid tumors such as melanoma, prostate cancer, and pancreatic cancer.
Cellular Localization Membrane
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Research Area Cancer antibody; Developmental Biology antibody; Immune System antibody
Calculated MW 57 kDa

Images (12) Click the Picture to Zoom In

  • ARG52539 anti-CD276 / B7-H3 antibody [SP206] WB image

    Western blot: 293T cell lysate stained with ARG52539 anti-CD276 / B7-H3 antibody [SP206].

  • ARG52539 anti-CD276 / B7-H3 antibody [SP206] IHC-P image

    Immunohistochemistry: Human testis stained with ARG52539 anti-CD276 / B7-H3 antibody [SP206].

  • ARG52539 anti-CD276 / B7-H3 antibody [SP206] IHC-P image

    Immunohistochemistry: Human stomach stained with ARG52539 anti-CD276 / B7-H3 antibody [SP206].

  • ARG52539 anti-CD276 / B7-H3 antibody [SP206] IHC-P image

    Immunohistochemistry: Human stomach adenocarcinoma stained with ARG52539 anti-CD276 / B7-H3 antibody [SP206].

  • ARG52539 anti-CD276 / B7-H3 antibody [SP206] IHC-P image

    Immunohistochemistry: Human Lung stained with ARG52539 anti-CD276 / B7-H3 antibody [SP206].

  • ARG52539 anti-CD276 / B7-H3 antibody [SP206] IHC-P image

    Immunohistochemistry: Human Lung Adenocarcinoma stained with ARG52539 anti-CD276 / B7-H3 antibody [SP206].

  • ARG52539 anti-CD276 / B7-H3 antibody [SP206] IHC-P image

    Immunohistochemistry: Human Lung SCCa stained with ARG52539 anti-CD276 / B7-H3 antibody [SP206].

  • ARG52539 anti-CD276 / B7-H3 antibody [SP206] IHC-P image

    Immunohistochemistry: Human Colon stained with ARG52539 anti-CD276 / B7-H3 antibody [SP206].

  • ARG52539 anti-CD276 / B7-H3 antibody [SP206] IHC-P image

    Immunohistochemistry: Human Colon Adenocarcinoma stained with ARG52539 anti-CD276 / B7-H3 antibody [SP206].

  • ARG52539 anti-CD276 / B7-H3 antibody [SP206] IHC-P image

    Immunohistochemistry: Human Breast stained with ARG52539 anti-CD276 / B7-H3 antibody [SP206].

  • ARG52539 anti-CD276 / B7-H3 antibody [SP206] IHC-P image

    Immunohistochemistry: Human Breast Ductal Carcinoma stained with ARG52539 anti-CD276 / B7-H3 antibody [SP206].

  • ARG52539 anti-CD276 / B7-H3 antibody [SP206] IHC-P image

    Immunohistochemistry: Human Tonsil stained with ARG52539 anti-CD276 / B7-H3 antibody [SP206].