ARG21040

anti-CD81 antibody [2F7] (azide free)

anti-CD81 antibody [2F7] (azide free) for Flow cytometry,Immunohistochemistry,ICC/IF,Immunoprecipitation,Blocking and Mouse

Overview

Product Description Azide free and low endotoxin Hamster Monoclonal antibody [2F7] recognizes CD81
Tested Reactivity Ms
Tested Application BL, FACS, ICC/IF, IHC, IP
Specificity Mouse CD81. The clone 2F7 can block thymocyte interaction with CD81 in vitro.
Host Hamster
Clonality Monoclonal
Clone 2F7
Isotype IgG3
Target Name CD81
Antigen Species Mouse
Immunogen Mouse epithelial cell line PAM212
Conjugation Un-conjugated
Full Name CD81 antigen
Alternate Names CD antigen CD81; TAPA1; Tspan-28; S5.7; CD81 antigen; Target of the antiproliferative antibody 1; Tetraspanin-28; 26 kDa cell surface protein TAPA-1; CVID6; TSPAN28

Application Instructions

Application Suggestion
Tested Application Dilution
BLAssay-dependent
FACSAssay-dependent
ICC/IFAssay-dependent
IHCAssay-dependent
IPAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Calculated MW 26 kDa

Properties

Form Liquid
Purification Note Low endotoxin
Buffer PBS
Concentration 0.5 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 12520 Mouse CD81

Swiss-port # P35762 Mouse CD81 antigen

Gene Symbol CD81
Gene Full Name CD81 antigen
Background The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Function May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May act as the viral receptor for HCV. [UniProt]
PTM Not glycosylated.