ARG10188

anti-CEA antibody [CEA-Y1]

anti-CEA antibody [CEA-Y1] for ELISA,Western blot and Human

Cancer antibody; Developmental Biology antibody; Controls and Markers antibody; Microbiology and Infectious Disease antibody

Overview

Product Description Mouse Monoclonal antibody [CEA-Y1] recognizes Human CEA
Tested Reactivity Hu
Tested Application ELISA, WB
Specificity Cross-reactivity with other human protein was not found.
Host Mouse
Clonality Monoclonal
Clone CEA-Y1
Isotype IgG1,k
Target Name CEA
Antigen Species Human
Immunogen Human carcinoembryonic antigen (CEA)
Conjugation Un-conjugated
Alternate Names Carcinoembryonic antigen-related cell adhesion molecule 5; CEA; CD66e; CD antigen CD66e; Carcinoembryonic antigen; Meconium antigen 100

Application Instructions

Application Note ELISA: this antibody can be used as capture antibody in sandwich ELISA for quantitative detection of CEA

Western Blot: 25 ng/lane of antigen can be detected when the antibody was used at 100 ng/ml.

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein G affinity purified
Buffer 0.01M PBS (pH 7.0)
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 1048 Human CEACAM5

Swiss-port # P06731 Human Carcinoembryonic antigen-related cell adhesion molecule 5

Gene Symbol CEACAM5
Gene Full Name carcinoembryonic antigen-related cell adhesion molecule 5
Background Carcinoembryonic Antigen (CEA) is a 180-200 KD glycoprotein expressed at high level in the epithelial cells of the embryonic colon. The expression is stopped after birth. CEA serum content is low in normal population and only slightly elevated in heavy smokers. Increased serum CEA level was found to be associated with colorectal carcinoma, gastric carcinoma, pancreatic carcinoma, lung carcinoma, and breast carcinoma. However elevated CEA level does not necessarily indicate neoplastic conditions. CEA level is useful for monitoring tumour recurrence after surgical resection of carcinoma.
Function Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins. [UniProt]
Resrarch Area Cancer antibody; Developmental Biology antibody; Controls and Markers antibody; Microbiology and Infectious Disease antibody
PTM Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.