ARG10018

anti-G-CSFR antibody [S1390]

anti-G-CSFR antibody [S1390] for Western blot and Human

Cancer antibody; Developmental Biology antibody; Immune System antibody

Overview

Product Description

Mouse Monoclonal antibody [S1390] recognizes GCSF Receptor

Tested Reactivity Hu
Tested Application WB
Host Mouse
Clonality Monoclonal
Clone S1390
Isotype IgG2b,k
Target Name G-CSF Receptor
Antigen Species Human
Immunogen Purified recombinant MBP-GCSFR fusion protein
Conjugation Un-conjugated
Alternate Names G-CSF receptor; CD114; CD antigen CD114; G-CSF-R; GCSFR; Granulocyte colony-stimulating factor receptor

Application Instructions

Application Note Western Blot: The antibody recognizes denatured G-CSFR in Western blot following SDS-PAGE. Suggest use 200μg of cell lysate or immunoprecipitated protein.

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein G affinity purified
Buffer 0.01M PBS (pH 7.2)
Concentration 1 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 1441 Human CSF3R

Swiss-port # Q99062 Human Granulocyte colony-stimulating factor receptor

Gene Symbol CSF3R
Gene Full Name colony stimulating factor 3 receptor (granulocyte)
Background The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010]
Function Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface. [UniProt]
Resrarch Area Cancer antibody; Developmental Biology antibody; Immune System antibody
PTM N-glycosylated.