ARG10162

anti-GH1 antibody [Gh29]

anti-GH1 antibody [Gh29] for ELISA and Human

Developmental Biology antibody; Signaling Transduction antibody

Overview

Product Description Mouse Monoclonal antibody [Gh29] recognizes GH1
Tested Reactivity Hu
Tested Application ELISA
Specificity There is no cross-reactivity with HPRL, FSH, LH and insulin.
Host Mouse
Clonality Monoclonal
Clone Gh29
Isotype IgG1
Target Name GH1
Antigen Species Human
Immunogen Purified recombinant hGH
Conjugation Un-conjugated
Alternate Names GH-N; Somatotropin; IGHD1B; Growth hormone; Growth hormone 1; Pituitary growth hormone; GHN; hGH-N; GH

Application Instructions

Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein G affinity purified.
Buffer PBS (pH 7.4) and 0.1% Sodium azide
Preservative 0.1% Sodium azide
Concentration 1.0-2.0 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 2688 Human GH1

Swiss-port # P01241 Human Somatotropin

Gene Symbol GH1
Gene Full Name growth hormone 1
Background The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. [provided by RefSeq, Jul 2008]
Function Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. [UniProt]
Resrarch Area Developmental Biology antibody; Signaling Transduction antibody