ARG21451

anti-IL13 antibody [JES10-5A2] (azide free)

anti-IL13 antibody [JES10-5A2] (azide free) for ELISA,ELISA,ELISPOT,Flow cytometry,IHC-Frozen sections,ICC/IF,Neutralizing and Human

Overview

Product Description Azide free and low endotoxin Rat Monoclonal antibody [JES10-5A2 ] recognizes IL13
Tested Reactivity Hu
Tested Application ELISA, ELISA, ELISPOT, FACS, ICC/IF, IHC-Fr, Neut
Specificity Human IL-13.
Host Rat
Clonality Monoclonal
Clone JES10-5A2
Isotype IgG1, kappa
Target Name IL13
Antigen Species Human
Immunogen COS-expressed human IL-13
Conjugation Un-conjugated
Full Name interleukin 13
Alternate Names Interleukin-13; P600; IL-13

Application Instructions

Application Suggestion
Tested Application Dilution
ELISA< 5 µg/ml
ELISA< 5 µg/ml
ELISPOTAssay-dependent
FACSAssay-dependent
ICC/IFAssay-dependent
IHC-FrAssay-dependent
NeutAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Calculated MW 16 kDa

Properties

Form Liquid
Purification Note Low endotoxin
Buffer PBS
Concentration 0.5 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 3596 Human IL13

Swiss-port # P35225 Human Interleukin-13

Gene Symbol IL13
Gene Full Name interleukin 13
Background This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
Function Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. [UniProt]