ARG10166

anti-NSE antibody [5A4]

anti-NSE antibody [5A4] for ELISA,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Cancer antibody; Gene Regulation antibody; Metabolism antibody; Signaling Transduction antibody

Overview

Product Description Mouse Monoclonal antibody [5A4] recognizes NSE
Tested Reactivity Hu
Tested Application ELISA, IHC-P, WB
Host Mouse
Clonality Monoclonal
Clone 5A4
Isotype IgG2a
Target Name NSE
Antigen Species Human
Immunogen Purified NSE from human brain.
Conjugation Un-conjugated
Full Name enolase 2 (gamma, neuronal)
Alternate Names Neural enolase; NSE; Enolase 2; Gamma-enolase; 2-phospho-D-glycerate hydro-lyase; HEL-S-279; Neuron-specific enolase; EC 4.2.1.11

Application Instructions

Application Note
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein G affinity purified.
Buffer PBS (pH 7.4) and 0.1% Sodium azide
Preservative 0.1% Sodium azide
Concentration 1.0-2.0 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 2026 Human ENO2

Swiss-port # P09104 Human Gamma-enolase

Gene Symbol ENO2
Background This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. [provided by RefSeq, Jul 2008]
Function Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity). [UniProt]
Highlight Related products:
NSE antibodies; Anti-Mouse IgG secondary antibodies;
Related news:
Neuronal Development Marker
Resrarch Area Cancer antibody; Gene Regulation antibody; Metabolism antibody; Signaling Transduction antibody

Clone References

Evidence that a panel of neurodegeneration biomarkers predicts vasospasm, infarction, and outcome in aneurysmal subarachnoid hemorrhage.

WB / Human

Siman R et al.
PLoS One.,  (2011)

publication_link

 

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Ionizing radiation induces prostate cancer neuroendocrine differentiation through interplay of CREB and ATF2: implications for disease progression.

WB / Human

Deng X et al.
Cancer Res.,  (2008)

publication_link

 

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Free antibody sample