anti-PPAR alpha antibody

anti-PPAR alpha antibody for Flow cytometry,ICC/IF,Immunohistochemistry,Western blot and Human,Mouse,Rat

Cancer antibody; Cell Biology and Cellular Response antibody; Gene Regulation antibody; Metabolism antibody
publication_link Publication3


Product Description Mouse Monoclonal antibody recognizes PPAR alpha
Tested Reactivity Hu, Ms, Rat
Tested Application FACS, ICC/IF, IHC, WB
Host Mouse
Clonality Monoclonal
Isotype IgG1, kappa
Target Name PPAR alpha
Antigen Species Human
Immunogen Recombination protein of Human PPAR alpha (Swiss: Q07869).
Conjugation Un-conjugated
Alternate Names hPPAR; NR1C1; Peroxisome proliferator-activated receptor alpha; PPAR; Nuclear receptor subfamily 1 group C member 1; PPAR-alpha; PPARalpha

Application Instructions

Application Suggestion
Tested Application Dilution
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Purification with Protein G.
Buffer PBS and 0.09% (W/V) Sodium azide
Preservative 0.09% (W/V) Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 19013 Mouse PPARA

GeneID: 25747 Rat PPARA

GeneID: 5465 Human PPARA

Gene Symbol PPARA
Gene Full Name peroxisome proliferator-activated receptor alpha
Background Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008]
Function Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2. [UniProt]
Cellular Localization Nucleus.
Research Area Cancer antibody; Cell Biology and Cellular Response antibody; Gene Regulation antibody; Metabolism antibody
Calculated MW 52 kDa

Images (3) Click the Picture to Zoom In

  • ARG55240 anti-PPAR alpha antibody WB image

    Western blot: 30 μg of HepG2, HEK293T, HCT116, NIH-3T3, Mouse brain, Rat brain and Rat ovary lysates stained with ARG55240 anti-PPAR alpha antibody at 1:500 dilution.

  • ARG55240 anti-PPAR alpha antibody ICC/IF image

    Immunofluorescence: HeLa cells stained with ARG55240 anti-PPAR alpha antibody (green) at 1:25 dilution. Cytoplasmic actin was counterstained with Alexa Fluor® 555 conjugated with Phalloidin (red).

  • ARG55240 anti-PPAR alpha antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human kidney tissue stained with ARG55240 anti-PPAR alpha antibody at 1:25 dilution.

Specific References

Diet suppresses glioblastoma initiation in mice by maintaining quiescence of mutation-bearing neural stem cells

ICC/IF / Mouse

Valeria Amodeo et al.
Dev Cell.,  (2023)




PCSK9Qβ-003 Vaccine Attenuates Atherosclerosis in Apolipoprotein E-Deficient Mice.

WB / Mouse

Danyu Wu et al.
Cardiovasc Drugs Ther.,  (2020)




Vaccine Against PCSK9 Improved Renal Fibrosis by Regulating Fatty Acid β-Oxidation.

WB / Mouse

Wu Danyu et al.
J Am Heart Assoc.,  (2020)