anti-PRL antibody [PRL-1]
anti-PRL antibody [PRL-1] for ELISA and Human
Signaling Transduction antibody
|Product Description||Mouse Monoclonal antibody [PRL-1] recognizes Human PRL|
|Immunogen||Human 23kDa prolactin|
|Alternate Names||Prolactin; PRL|
|Application Note||ELISA: In combination with our matched anti-PRL tracer antibody (anti- human PRL antibody, HRP-conjugated, Cat No: ARG10176), this antibody can be used as capture antibody in sandwich ELISA for human PRL detection. The suggested coating concentration is 4μg/ml.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
|Purification||Protein G affinity purified|
|Buffer||0.01M PBS (pH 7.2)|
|Storage instruction||For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.|
|Note||For laboratory research only, not for drug, diagnostic or other use.|
|Background||Prolactin (PRL) is primarily secreted by pituitary gland. The hormone stimulates mammary gland development during pregnancy and lactation after childbirth. PRL has several variations with molecular weights ranged from 22kDa to 150kDa. PRL receptors are mainly located at mammary glands, and also found in other organs and tissues. PRL can bind to cytokine-like receptors and influence haematopoiesis, angiogenesis, and immuno-system. Anterior pituitary tumours can cause persistent elevation of PRL with clinical signs such as abnormal lactation, infertility and lack of menstrual flow in women, and incompetence in men.|
|Function||Prolactin acts primarily on the mammary gland by promoting lactation. [UniProt]|
|Resrarch Area||Signaling Transduction antibody|