anti-PRL antibody [PRL-2] (HRP)
anti-PRL antibody [PRL-2] (HRP) for ELISA and Human
Signaling Transduction antibody
|Product Description||HRP-conjugated Mouse Monoclonal antibody [PRL-2] recognizes Human PRL|
|Alternate Names||Prolactin; PRL|
|Application Note||ELISA: In combination with anti-PRL capture antibody (Cat No: ARG10175), this HRP conjugated antibody can be used as tracer in sandwich ELISA for human PRL detection.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
|Purification||Protein G affinity purified|
|Buffer||0.01M PBS (pH 7.2) and 50% Glycerol|
|Storage instruction||For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Keep the antibody in the dark and keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.|
|Note||For laboratory research only, not for drug, diagnostic or other use.|
|Background||Prolactin (PRL) is primarily secreted by pituitary gland. The hormone stimulates mammary gland development during pregnancy and lactation after childbirth. PRL has several variations with molecular weights ranged from 22kDa to 150kDa. PRL receptors are mainly located at mammary glands, but also found in other organs and tissues. PRL can bind to cytokine-like receptors and influence haematopoiesis, angiogenesis, and immuno-system. Anterior pituitary tumours can cause persistent elevation of PRL with clinical signs such as abnormal lactation, infertility and lack of menstrual flow in women, and incompetence in men.|
|Function||Prolactin acts primarily on the mammary gland by promoting lactation. [UniProt]|
|Resrarch Area||Signaling Transduction antibody|