anti-ROR gamma antibody [SQab30332]

anti-ROR gamma antibody [SQab30332] for IHC-Formalin-fixed paraffin-embedded sections and Human


Product Description Recombinant rabbit Monoclonal antibody [SQab30332] recognizes ROR gamma
Tested Reactivity Hu
Tested Application IHC-P
Host Rabbit
Clonality Monoclonal
Clone SQab30332
Isotype IgG
Target Name ROR gamma
Antigen Species Human
Immunogen Synthetic peptide of Human ROR gamma
Conjugation Un-conjugated
Protein Full Name Nuclear receptor ROR-gamma
Alternate Names RORC, RAR Related Orphan Receptor C, NR1F3, RZRG, RORG, TOR, Nuclear Receptor Subfamily 1 Group F Member 3, RAR-Related Orphan Receptor C, Nuclear Receptor ROR-Gamma, Nuclear Receptor RZR-Gamma, Retinoid-Related Orphan Receptor Gamma, Retinoid-Related Orphan Receptor-Gamma, Retinoic Acid-Binding Receptor Gamma, RZR-GAMMA, IMD42

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:100
Application Note IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0). Incubate the samples at RT (18-25°C) for 44 min.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Tonsil


Form Liquid
Purification Purification with Protein A.
Buffer PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA.
Preservative 0.01% Sodium azide
Stabilizer 40% Glycerol and 0.05%BSA
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Gene Symbol RORC
Gene Full Name RAR Related Orphan Receptor C
Background The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of cellular differentiation, immunity, peripheral circadian rhythm as well as lipid, steroid, xenobiotics and glucose metabolism. [UniProt]
Cellular Localization Nucleus
Calculated MW 58 kDa

Images (1) Click the Picture to Zoom In

  • ARG67045 anti-ROR gamma antibody [SQab30332] IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded tonsil stained with ARG67045 anti-ROR gamma antibody [SQab30332].