ARG10179

anti-hCG antibody [HCG-1]

anti-hCG antibody [HCG-1] for ELISA and Human

Cancer antibody; Developmental Biology antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody

Overview

Product Description Mouse Monoclonal antibody [HCG-1] recognizes Human chorionic gonadotropin (hCG)
Tested Reactivity Hu
Tested Application ELISA
Host Mouse
Clonality Monoclonal
Clone HCG-1
Isotype IgG1,k
Target Name hCG
Immunogen Purified human chorionic gonadotropin from urine
Conjugation Un-conjugated
Full Name chorionic gonadotropin, beta polypeptide
Alternate Names hCGB; CGB5; CGB7; CGB3; Chorionic gonadotrophin chain beta; CGB8; CG-beta; Choriogonadotropin subunit beta

Application Instructions

Application Note ELISA: This antibody can be used as capturer in Sandwich ELISA for quantitative determination of HCG in combination with HRP conjugated anti-HCG β subunit antibody (Cat No: ARG10180).

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein G affinity purified
Buffer 0.01M PBS (pH 7.2)
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 1082 Human CGB

Swiss-port # P01233 Human Choriogonadotropin subunit beta

Gene Symbol CGB
Background Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by placenta after conception. hCG is comprised of a α subunit with 92 amino acids and a β subunit with 245 amino acids. The α subunit is identical to that of LH (Luteinizing hormone), FSH (Follicle-stimulating hormone) and TSH (Thyroid-stimulating hormone). hCG sustains corpus luteum, stimulats progesterone secretion, hence is critical to early foetus development. It has also been reported that hCG plays a role in the development of foetus’s tolerance to maternal immunity. hCG is the most sensitive biomarker for pregnancy.
Function Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. [UniProt]
Resrarch Area Cancer antibody; Developmental Biology antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody

Clone References

BMP4 initiates human embryonic stem cell differentiation to trophoblast.

Xu RH et al.
Nat Biotechnol.,  (2002)

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Time-resolved fluoroimmunoassay of human choriogonadotropin.

Pettersson K et al.
Clin Chem.,  (1983)

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hr_line

The use of monoclonal antibodies against human chorionic gonadotropin for immunoperoxidase staining of normal placenta, pituitary gland, and pituitary adenomas.

Wahlström T et al.
J Histochem Cytochem.,  (1981)

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hr_line

Latex-based thin-layer immunoaffinity chromatography for quantitation of protein analytes.

Birnbaum S et al.
Anal Biochem.,  (1992)

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Free antibody sample