ARG81251

Human BDNF ELISA Kit

Human BDNF ELISA Kit for ELISA and Human

Overview

Product Description

ARG81251 Human BDNF ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human BDNF in serum, plasma or cell culture supernatants.

Tested Reactivity Hu
Tested Application ELISA
Target Name BDNF
Conjugation HRP
Conjugation Note

Substrate: TMB and read at 450 nm.

Sensitivity 7 pg/ml
Sample Type Serum, plasma or cell culture supernatants.
Standard Range 15.625 - 1000 pg/ml
Sample Volume 100 µl
Alternate Names Brain-derived neurotrophic factor; Abrineurin; BULN2; ANON2; BDNF

Application Instructions

Assay Time ~ 3.5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 627 Human BDNF

Swiss-port # P23560 Human Brain-derived neurotrophic factor

Gene Symbol BDNF
Gene Full Name brain-derived neurotrophic factor
Background The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jan 2009]
Function During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. [UniProt]
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PTM The propeptide is N-glycosylated and glycosulfated.
Converted into mature BDNF by plasmin (PLG).

Images (1) Click the Picture to Zoom In

  • ARG81251 Human BDNF ELISA Kit standard curve image

    ARG81251 Human BDNF ELISA Kit results of a typical standard run with optical density reading at 450 nm.

Title Download Link
ARG81251 Human BDNF ELISA Kit User's manual download icon Download