Mouse FGF basic ELISA Kit
Mouse FGF basic ELISA Kit for ELISA and Mouse
ARG81276 Mouse FGF basic ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse FGF basic in serum, plasma or cell culture supernatants.
|Target Name||FGF basic|
Substrate: TMB and read at 450 nm.
|Sample Type||Serum, plasma or cell culture supernatants.|
|Standard Range||46.875 - 3000 pg/ml|
|Sample Volume||100 µl|
|Alternate Names||FGF-2; Fibroblast growth factor 2; bFGF; FGFB; Heparin-binding growth factor 2; BFGF; HBGF-2; Basic fibroblast growth factor|
|Assay Time||~ 3.5 hours|
|Storage Instruction||Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.|
|Note||For laboratory research only, not for drug, diagnostic or other use.|
|Gene Full Name||fibroblast growth factor 2|
|Background||The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq, Jul 2008]|
|Function||Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. [UniProt]|
FGF basic antibodies; FGF basic ELISA Kits; FGF basic recombinant proteins;
The role of HDGF in tumor angiogenesis
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|PTM||Phosphorylation at Tyr-215 regulates FGF2 unconventional secretion.
Several N-termini starting at positions 94, 125, 126, 132, 143 and 162 have been identified by direct sequencing.
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|ARG81276 Mouse FGF basic ELISA Kit User's manual||Download|