ARG59824

anti-PRPF31 / RP11 antibody

anti-PRPF31 / RP11 antibody for Western blot and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes PRPF31 / RP11
Tested Reactivity Hu, Ms
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name PRPF31 / RP11
Antigen Species Human
Immunogen Synthetic peptide of Human PRPF31.
Conjugation Un-conjugated
Full Name pre-mRNA processing factor 31
Alternate Names U4/U6 small nuclear ribonucleoprotein Prp31; Pre-mRNA-processing factor 31; NY-BR-99; Serologically defined breast cancer antigen NY-BR-99; PRP31; hPrp31; Protein 61K; U4/U6 snRNP 61 kDa protein; SNRNP61; RP11

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control NIH/3T3 and HeLa
Calculated MW 55 kDa
Observed Size 55 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3) and 0.02% Sodium azide.
Preservative 0.02% Sodium azide
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 26121 Human PRPF31

GeneID: 68988 Mouse PRPF31

Swiss-port # Q8CCF0 Mouse U4/U6 small nuclear ribonucleoprotein Prp31

Swiss-port # Q8WWY3 Human U4/U6 small nuclear ribonucleoprotein Prp31

Gene Symbol PRPF31
Gene Full Name pre-mRNA processing factor 31
Background This gene encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes. When the gene product is added to the spliceosome complex, activation occurs.[provided by RefSeq, Jan 2009]
Function Involved in pre-mRNA splicing. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. [UniProt]
Cellular Localization Nucleus. Nucleus speckle. Nucleus, Cajal body. Note=Predominantly found in speckles and in Cajal bodies. [UniProt]
Highlight Related products:
PRPF31 antibodies; Anti-Rabbit IgG secondary antibodies;
Related news:
Gene therapy for retinitis pigmentosa (RP)

Images (1) Click the Picture to Zoom In

  • ARG59824 anti-PRPF31 / RP11 antibody WB image

    Western blot: 25 µg of NIH/3T3 and HeLa cell lysates stained with ARG59824 anti-PRPF31 / RP11 antibody at 1:1000 dilution.