ARG59787

anti-PRPF4 antibody

anti-PRPF4 antibody for Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes PRPF4
Tested Reactivity Hu, Ms, Rat
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name PRPF4
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 1-260 of Human PRPF4 (NP_004688.2).
Conjugation Un-conjugated
Alternate Names RP70; U4/U6 snRNP 60 kDa protein; HPRP4P; WD splicing factor Prp4; PRP4; U4/U6 small nuclear ribonucleoprotein Prp4; PRP4 homolog; Prp4p; SNRNP60; hPrp4; HPRP4

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Rat spleen, Mouse testis and MCF7
Observed Size 58 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 70052 Mouse PRPF4

GeneID: 9128 Human PRPF4

Swiss-port # O43172 Human U4/U6 small nuclear ribonucleoprotein Prp4

Swiss-port # Q9DAW6 Mouse U4/U6 small nuclear ribonucleoprotein Prp4

Gene Symbol PRPF4
Gene Full Name pre-mRNA processing factor 4
Background The protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Function Participates in pre-mRNA splicing. Part of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. [UniProt]
Cellular Localization Nucleus speckle. Note=Colocalizes with spliceosomal snRNPs. [UniProt]
Highlight Related products:
PRPF4 antibodies; Anti-Rabbit IgG secondary antibodies;
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Calculated MW 58 kDa

Images (1) Click the Picture to Zoom In

  • ARG59787 anti-PRPF4 antibody WB image

    Western blot: 25 µg of Rat spleen, Mouse testis and MCF7 cell lysates stained with ARG59787 anti-PRPF4 antibody at 1:1000 dilution.