anti-TRAP1 antibody [Trap1-6] (Biotin)

anti-TRAP1 antibody [Trap1-6] (Biotin) for ICC/IF and Human


Product Description Biotin-conjugated Mouse Monoclonal antibody [Trap1-6] recognizes TRAP1
Tested Reactivity Hu
Tested Application ICC/IF
Host Mouse
Clonality Monoclonal
Clone Trap1-6
Isotype IgG2a, kappa
Target Name TRAP1
Antigen Species Human
Immunogen Recombinant protein of Human TRAP1.
Conjugation Biotin
Alternate Names HSP90L; Tumor necrosis factor type 1 receptor-associated protein; TRAP-1; TNFR-associated protein 1; Heat shock protein 75 kDa, mitochondrial; HSP 75; HSP75

Application Instructions

Application Suggestion
Tested Application Dilution
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Purification with Protein G.
Buffer PBS (pH 7.4), 0.09% azide and 50% Glycerol.
Preservative 0.09% azide
Stabilizer 50% Glycerol
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Keep the antibody in the dark and keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 10131 Human TRAP1

Swiss-port # Q12931 Human Heat shock protein 75 kDa, mitochondrial

Gene Symbol TRAP1
Gene Full Name TNF receptor-associated protein 1
Background This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Function Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA. [UniProt]
Calculated MW 80 kDa