ARG70636
Hantaan Virus nucleocapsid peptide
Hantaan Virus nucleocapsid peptide for Blocking
Overview
| Product Description | The peptide is used for blocking the activity of anti-Hantaan Virus nucleocapsid antibody ARG46772 |
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| Tested Application | BL |
| Target Name | Hantaan Virus nucleocapsid |
| A.A. Sequence | 18 amino acids near the amino terminus of the Hantaan virus nucleocapsid. |
Application Instructions
| Application Suggestion |
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| Application Note | This peptide usually blocks anti-Hantaan Virus nucleocapsid antibody ARG46772 activity completely by incubating the peptide with equal volume of antibody for 30 min at at 37°C. |
Properties
| Form | Liquid |
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| Buffer | PBS (pH 7.2), 0.02% sodium azide and 0.1% BSA |
| Concentration | 200 µg/ml |
| Storage Instruction | Store peptide at -20°C, stable for one year. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Background | Hantaan virus (HNTV) is the prototype virus of the genus hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA virus that is the eiological agent of Korean hemorrhagic fever (1). Infection of cultured Vero E6 cells with HNTV induced expression of the heat shock protein HSP70. A substantial fraction of HSP70 was found to be associated with the HNTV nucleocapsid (NP) (2). Vero E6 cells that overexpress HSP70 show significantly reduced levels of NP and an increased resistance to infection by HNTV (2). |
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