ARG70608
Human CCL1 / I-309 recombinant protein (Active)
Human CCL1 / I-309 recombinant protein (Active) for SDS-PAGE
Overview
| Product Description | E. coli expressed, Active Human CCL1 / I-309 recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | CCL1 / I-309 |
| Species | Human |
| A.A. Sequence | Ser23 - Lys96 |
| Expression System | E. coli |
| Activity | Active |
| Activity Note | Determined by a chemotaxis bioassay using human T- lymphocytes is in a concentration range of 10 - 100 ng/ml. |
| Alternate Names | TCA3; T lymphocyte-secreted protein I-309; SISe; P500; Small-inducible cytokine A1; I-309; SCYA1; C-C motif chemokine 1 |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | > 98% (by SDS-PAGE or HPLC). |
| Buffer | 20 mM PB, with 150 mM NaCl (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | CCL1 |
|---|---|
| Gene Full Name | chemokine (C-C motif) ligand 1 |
| Background | This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8. [provided by RefSeq, Sep 2014] |
| Function | Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8. [UniProt] |
