ARG70920
Human CCL16 / LEC recombinant protein (His-tagged and SUMO-tagged, N-ter)
Human CCL16 / LEC recombinant protein (His-tagged and SUMO-tagged, N-ter) for SDS-PAGE
Overview
| Product Description | HEK293 expressed, Human His-tagged and SUMO-tagged (N-ter) CCL16 / LEC recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | CCL16 / LEC |
| Species | Human |
| A.A. Sequence | Gln24 - Gln120 |
| Expression System | HEK293 |
| Alternate Names | CKb12; HCC-4; LEC; Monotactin-1; SCYA16; Chemokine LEC; MTN-1; SCYL4; Mtn-1; Lymphocyte and monocyte chemoattractant; Small-inducible cytokine A16; Liver-expressed chemokine; IL-10-inducible chemokine; C-C motif chemokine 16; NCC4; LCC-1; ILINCK; LMC; Chemokine CC-4; NCC-4 |
Properties
| Form | Powder |
|---|---|
| Buffer | PBS |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration approximately 1 mg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C, protected from light and moisture, for up to 12 months. After reconstitution , aliquot and store at 2 to 8°C for up to 2 days, or at -20°C or -80°C for up to 3 months Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
Bioinformation
| Gene Symbol | CCL16 |
|---|---|
| Gene Full Name | chemokine (C-C motif) ligand 16 |
| Background | This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for lymphocytes and monocytes but not for neutrophils. This cytokine also shows a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. The expression of this gene is upregulated by IL-10. [provided by RefSeq, Jul 2008] |
| Function | Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES. [UniProt] |
