ARG70603
Human CD22 recombinant protein (His-tagged, C-ter)
Human CD22 recombinant protein (His-tagged, C-ter) for SDS-PAGE and Human
Overview
| Product Description | CHO expressed, His-tagged (C-ter) Human CD22 recombinant protein |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | SDS-PAGE |
| Target Name | CD22 |
| Species | Human |
| A.A. Sequence | Met 1-Arg 687 |
| Expression System | CHO |
| Alternate Names | CD22; CD22 Molecule; SIGLEC2; CD22 Antigen; SIGLEC-2; Sialic Acid-Binding Ig-Like Lectin 2; B-Lymphocyte Cell Adhesion Molecule; T-Cell Surface Antigen Leu-14; B-Cell Receptor CD22; BL-CAM; Sialic Acid Binding Ig-Like Lectin 2; Siglec-2 |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is<0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | > 95% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CD22 |
| Gene Full Name | CD22 Molecule |
| Background | Predicted to enable CD4 receptor binding activity; protein phosphatase binding activity; and sialic acid binding activity. Involved in B cell activation; negative regulation of B cell receptor signaling pathway; and regulation of endocytosis. Located in early endosome and recycling endosome. Implicated in diffuse large B-cell lymphoma. [provided by Alliance of Genome Resources, Nov 2024] |
| Function | If this negative signaling from is of sufficient strength, apoptosis of the B-cell can be induced. [Uniprot] |
