ARG70660

Human CD223 / LAG3 recombinant protein (His-tagged, C-ter)

Human CD223 / LAG3 recombinant protein (His-tagged, C-ter) for SDS-PAGE

Overview

Product Description HEK293 expressed, His-tagged (C-ter) Human CD223 / LAG3 recombinant protein
Tested Application SDS-PAGE
Target Name CD223 / LAG3
Species Human
A.A. Sequence Met1 - Leu450
Expression System HEK293
Alternate Names CD antigen CD223; CD223; Protein FDC; Lymphocyte activation gene 3 protein; LAG-3

Properties

Form Powder
Purification Note Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test.
Purity > 95% (by SDS-PAGE)
Buffer PBS (pH 7.4)
Reconstitution It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely.
Storage Instruction For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol Lag3
Gene Full Name lymphocyte-activation gene 3
Background Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008]
Function Involved in lymphocyte activation. Binds to HLA class-II antigens. [UniProt]