ARG70755
Human CLEC2 / CLEC1B recombinant protein (His-tagged, C-ter)
Human CLEC2 / CLEC1B recombinant protein (His-tagged, C-ter) for SDS-PAGE
Overview
| Product Description | CHO expressed, His-tagged (C-ter) Human CLEC2 / CLEC1B recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | CLEC2 / CLEC1B |
| Species | Human |
| A.A. Sequence | Met53 - Leu229 |
| Expression System | CHO |
| Alternate Names | CLEC2; C-type lectin domain family 1 member B; CLEC2B; PRO1384; C-type lectin-like receptor 2; CLEC-2; 1810061I13Rik; QDED721 |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | > 90% (by SDS-PAGE); > 95% (by HPLC) |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | CLEC1B |
|---|---|
| Gene Full Name | C-type lectin domain family 1, member B |
| Background | Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011] |
| PTM | Glycosylated. Phosphorylated on tyrosine residue in response to rhodocytin binding. [UniProt] |
