ARG70899
Human Cathepsin S recombinant protein (MBP-tagged, N-ter / His-tagged, C-ter)
Human Cathepsin S recombinant protein (MBP-tagged, N-ter / His-tagged, C-ter) for SDS-PAGE
Overview
| Product Description | E. coli expressed, Human MBP-tagged (N-ter) / His-tagged (C-ter) Cathepsin S recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | Cathepsin S |
| Species | Human |
| A.A. Sequence | Leu115 - Ile331 |
| Expression System | E. coli |
| Alternate Names | Cathepsin S; EC 3.4.22.27 |
Properties
| Form | Powder |
|---|---|
| Buffer | PBS |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration approximately 1 mg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C, protected from light and moisture, for up to 12 months. After reconstitution , aliquot and store at 2 to 8°C for up to 2 days, or at -20°C or -80°C for up to 3 months Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
Bioinformation
| Gene Symbol | CTSS |
|---|---|
| Gene Full Name | cathepsin S |
| Background | The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The encoded protein can function as an elastase over a broad pH range in alveolar macrophages. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010] |
| Function | Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. [UniProt] |
| Cellular Localization | Lysosome. [UniProt] |
