ARG70617
Human Eotaxin 3 recombinant protein (Active)
Human Eotaxin 3 recombinant protein (Active) for SDS-PAGE
Overview
| Product Description | E. coli expressed, Active Human Eotaxin 3 recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | Eotaxin 3 |
| Species | Human |
| A.A. Sequence | Thr24 - Leu94 |
| Expression System | E. coli |
| Activity | Active |
| Activity Note | Determined by a chemotaxis bioassay using human CCR3 transfected HEK293 cells is in a concentration range of 0.5- 2.0 μg/ml. |
| Alternate Names | TSC-1; Eotaxin-3; SCYA26; IMAC; MIP-4a; MIP-4-alpha; Small-inducible cytokine A26; Macrophage inflammatory protein 4-alpha; MIP-4alpha; C-C motif chemokine 26; CC chemokine IMAC; Thymic stroma chemokine-1 |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | > 97% (by SDS-PAGE or HPLC). |
| Buffer | 20 mM PB, with 150 mM NaCl (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | CCL26 |
|---|---|
| Gene Full Name | chemokine (C-C motif) ligand 26 |
| Background | This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2008] |
| Function | Chemotactic for eosinophils and basophils. Binds to CCR3. [UniProt] |
