ARG83881

Human GDF10 ELISA Kit

Human GDF10 ELISA Kit for ELISA and Human

Overview

Product Description ARG83881 Human GDF10 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human GDF10 in serum, plasma, tissue homogenates, cell lysates, cell culture supernates
Tested Reactivity Hu
Tested Application ELISA
Target Name GDF10
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 19.34 pg/mL
Sample Type serum, plasma, tissue homogenates, cell lysates, cell culture supernates
Standard Range 31.25-2000 pg/mL
Sample Volume 100 μL
Precision Intra-Assay CV: < 8%
Inter-Assay CV: < 10%
Alternate Names BMP-3B; BMP3B; Bone Morphogenetic Protein 3B

Application Instructions

Assay Time 3.5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol GDF10
Gene Full Name Growth Differentiation Factor 10
Background This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This promotes neural repair after stroke. Additionally, this protein may act as a tumor suppressor and reduced expression of this gene is associated with oral cancer. [provided by RefSeq, Jul 2016]
Function Growth factor involved in osteogenesis and adipogenesis. Plays an inhibitory role in the process of osteoblast differentiation via SMAD2/3 pathway. Plays an inhibitory role in the process of adipogenesis. [UniProt]
Cellular Localization Secreted. [UniProt]
PTM Cleavage on pair of basic residues; Disulfide bond; Glycoprotein[UniProt]

Images (1) Click the Picture to Zoom In

  • ARG83881 Human GDF10 ELISA Kit standard curve image

    ARG83881 Human GDF10 ELISA Kit results of a typical standard run with optical density reading at 450 nm.

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