ARG70654
Human IGFBP7 recombinant protein (His-tagged, C-ter)
Human IGFBP7 recombinant protein (His-tagged, C-ter) for SDS-PAGE
Overview
| Product Description | HEK293 expressed, His-tagged (C-ter) Human IGFBP7 recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | IGFBP7 |
| Species | Human |
| A.A. Sequence | Ser27 - Leu282 |
| Expression System | HEK293 |
| Alternate Names | AGM; RAMSVPS; IBP-7; PSF; IGFBP-7; FSTL2; Tumor-derived adhesion factor; Insulin-like growth factor-binding protein 7; IGFBPRP1; TAF; MAC25; PGI2-stimulating factor; IGFBP-rP1; IGF-binding protein 7; IGFBP-7v; MAC25 protein; Prostacyclin-stimulating factor |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is less than 1 EU/µg of the protein, as determined by the LAL test. |
| Purity | > 95% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | IGFBP7 |
|---|---|
| Gene Full Name | insulin-like growth factor binding protein 7 |
| Background | This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011] |
| Function | Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. [UniProt] |
| PTM | N-glycosylated. |
