ARG80139

Human IL11 ELISA Kit

Human IL11 ELISA Kit for ELISA and Human

Cancer kit; Cell Biology and Cellular Response kit; Developmental Biology kit; Immune System kit

Component

Cat No Component Name Package Temp
ARG80139-001 Antibody-coated microplate 8 X 12 strips 4°C. Unused strips should be sealed tightly in the air-tight pouch.
ARG80139-002 Standard (Lyophilized) 3 X 2 ng/vial 4°C
ARG80139-003 Standard diluent buffer 20 ml 4°C
ARG80139-004 Antibody conjugate concentrate 400 µl 4°C
ARG80139-005 Antibody diluent buffer 16 ml 4°C
ARG80139-006 HRP-Streptavidin concentrate 400 µl 4°C (Protect from light)
ARG80139-007 HRP-Streptavidin diluent buffer 16 ml 4°C
ARG80139-008 20X Wash buffer 50 ml 4°C
ARG80139-009 TMB substrate 12ml 4°C (Protect from light)
ARG80139-010 STOP solution 12ml 4°C
ARG80139-011 Plate sealer 4 strips Room temperature

Overview

Product Description ARG80139 Human IL11 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human IL11 in Serum, Plasma, Cell culture supernatants.
Tested Reactivity Hu
Tested Application ELISA
Specificity No significant cross-reactivity or interference with Human Cardiotrophin-1, IL-6, OSM, CNTF, LIF, G-CSF Leptin
Target Name IL11
Conjugation HRP
Conjugation Note

Substrate: TMB and read at 450 nm

Sensitivity 15 pg/ml
Sample Type Serum, Plasma, Cell culture supernatants
Standard Range 31.25 - 2000 pg/ml
Sample Volume 100 µl
Precision

CV: <10%

Full Name interleukin 11
Alternate Names Oprelvekin; Interleukin-11; AGIF; Adipogenesis inhibitory factor; IL-11

Application Instructions

Assay Time 4 hours

Properties

Form 96 well
Storage instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol IL11
Gene Full Name interleukin 11
Background The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
Function Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. [UniProt]
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IL11 antibodies; IL11 ELISA Kits;
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Research Area Cancer kit; Cell Biology and Cellular Response kit; Developmental Biology kit; Immune System kit

Images (1) Click the Picture to Zoom In

  • ARG80139 Human IL11 ELISA Kit standard curve image

    ARG80139 Human IL11 ELISA Kit results of a typical standard run with optical density reading at 450 nm.

Title Download Link
ARG80139 Human IL11 ELISA Kit User's manual download icon Download