ARG70906
Human IL2 Receptor beta recombinant protein (His-tagged, C-ter)
Human IL2 Receptor beta recombinant protein (His-tagged, C-ter) for SDS-PAGE
Overview
| Product Description | HEK293 expressed, His-tagged (C-ter) IL2 Receptor beta recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | IL2 Receptor beta |
| Species | Human |
| A.A. Sequence | Thr31 - Arg230 |
| Expression System | HEK293 |
| Alternate Names | P70-75; IL-2RB; IL-2 receptor subunit beta; p75; Interleukin-2 receptor subunit beta; CD122; CD antigen CD122; High affinity IL-2 receptor subunit beta; IL-2R subunit beta; p70-75; IL15RB |
Properties
| Form | Powder |
|---|---|
| Buffer | PBS |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration approximately 1 mg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C, protected from light and moisture, for up to 12 months. After reconstitution , aliquot and store at 2 to 8°C for up to 2 days, or at -20°C or -80°C for up to 3 months Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
Bioinformation
| Gene Symbol | Il2rb |
|---|---|
| Gene Full Name | interleukin 2 receptor, beta chain |
| Background | The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq, Jul 2008] |
| Function | Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. [UniProt] |
