ARG70901
Human PRELP recombinant protein (MBP-tagged, N-ter / His-tagged, C-ter)
Human PRELP recombinant protein (MBP-tagged, N-ter / His-tagged, C-ter) for SDS-PAGE
Overview
| Product Description | HEK293 expressed, Human MBP-tagged (N-ter) / His-tagged (C-ter) PRELP recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | PRELP |
| Species | Human |
| A.A. Sequence | Gln21 - Ile382 |
| Expression System | HEK293 |
| Alternate Names | MST161; SLRR2A; Prolargin; Proline-arginine-rich end leucine-rich repeat protein; MSTP161 |
Properties
| Form | Powder |
|---|---|
| Buffer | PBS |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration approximately 1 mg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C, protected from light and moisture, for up to 12 months. After reconstitution , aliquot and store at 2 to 8°C for up to 2 days, or at -20°C or -80°C for up to 3 months Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
Bioinformation
| Gene Symbol | PRELP |
|---|---|
| Gene Full Name | proline/arginine-rich end leucine-rich repeat protein |
| Background | The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008] |
| Function | May anchor basement membranes to the underlying connective tissue. [UniProt] |
| Cellular Localization | Secreted, extracellular space, extracellular matrix. [UniProt] |
