ARG83879
Human S100A1 ELISA Kit
Human S100A1 ELISA Kit for ELISA and Human
Overview
| Product Description | ARG83879 Human S100A1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human S100A1 in Serum, Plasma, Tissue homogenates |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Target Name | S100A1 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 0.156 ng/ml |
| Sample Type | Serum, Plasma, Tissue homogenates |
| Standard Range | 0.312 ng/ml - 20 ng/ml |
| Sample Volume | 100 μl |
| Alternate Names | S100-alpha; S100; S100A |
Application Instructions
| Assay Time | 3.5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | S100A1 |
|---|---|
| Gene Full Name | S100 Calcium Binding Protein A1 |
| Background | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008] |
| Function | Small calcium binding protein that plays important roles in several biological processes such as Ca(2+) homeostasis, chondrocyte biology and cardiomyocyte regulation. In response to an increase in intracellular Ca(2+) levels, binds calcium which triggers conformational changes. Regulates a network in cardiomyocytes controlling sarcoplasmic reticulum Ca(2+) cycling and mitochondrial function through interaction with RYR1, RYR2, ATP2A2 and mitochondrial F1-ATPase. Facilitates diastolic Ca(2+) dissociation and myofilament mechanics in order to improve relaxation during diastole. [UniProt] |
| Cellular Localization | Cytoplasm; Sarcoplasmic reticulum; Mitochondrion; Nucleus. [UniProt] |
| PTM | S-nitrosylated; Phosphorylated. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG83879 Human S100A1 ELISA Kit standard curve image
ARG83879 Human S100A1 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG83879 Human S100A1 ELISA Kit |
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