ARG70883
Human SNRNP70 recombinant protein (His-tagged, C-ter)
Human SNRNP70 recombinant protein (His-tagged, C-ter) for SDS-PAGE
Overview
| Product Description | E. coli expressed, His-tagged (C-ter) SNRNP70 recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | SNRNP70 |
| Species | Human |
| A.A. Sequence | Ala11 - Arg180 |
| Expression System | E. coli |
| Alternate Names | RPU1; U1 snRNP 70 kDa; snRNP70; U1RNP; Snp1; RNPU1Z; U1-70K; SNRP70; U1AP; U1 small nuclear ribonucleoprotein 70 kDa; U170K |
Properties
| Form | Powder |
|---|---|
| Buffer | PBS |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration approximately 1 mg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C, protected from light and moisture, for up to 12 months. After reconstitution , aliquot and store at 2 to 8°C for up to 2 days, or at -20°C or -80°C for up to 3 months Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
Bioinformation
| Gene Symbol | SNRNP70 |
|---|---|
| Gene Full Name | small nuclear ribonucleoprotein 70kDa (U1) |
| Function | Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA. [UniProt] |
| Cellular Localization | Nucleus. Nucleus speckle. Nucleus, nucleoplasm. Note=Colocalizes with SCNM1 and LUC7L2 in nuclear speckles. [UniProt] |
| PTM | The N-terminus is blocked. Extensively phosphorylated on serine residues in the C-terminal region. [UniProt] |
