ARG70870

Human SOX18 recombinant protein (His-tagged, C-ter)

Human SOX18 recombinant protein (His-tagged, C-ter) for SDS-PAGE

Overview

Product Description E. coli expressed, His-tagged (C-ter) SOX18 recombinant protein
Tested Application SDS-PAGE
Target Name SOX18
Species Human
A.A. Sequence Ala91 - Pro170
Expression System E. coli
Alternate Names HLTRS; Transcription factor SOX-18; HLTS

Properties

Form Powder
Buffer PBS
Reconstitution It is recommended to reconstitute the lyophilized protein in sterile water to a concentration approximately 1 mg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely.
Storage Instruction For long term, lyophilized protein should be stored at -20°C or -80°C, protected from light and moisture, for up to 12 months. After reconstitution , aliquot and store at 2 to 8°C for up to 2 days, or at -20°C or -80°C for up to 3 months Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.

Bioinformation

Gene Symbol SOX18
Gene Full Name SRY (sex determining region Y)-box 18
Background This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia. [provided by RefSeq, Jul 2008]
Function Binds to the consensus sequence 5'-AACAAAG-3' and is able to trans-activate transcription via this site. [UniProt]
Cellular Localization Nucleus. [UniProt]