ARG70794
Human TROP2 recombinant protein (Active) (His-tagged, C-ter)
Human TROP2 recombinant protein (Active) (His-tagged, C-ter) for SDS-PAGE
Overview
| Product Description | CHO expressed, His-tagged (C-ter) Active Human TROP2 recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | TROP2 |
| Species | Human |
| A.A. Sequence | Met1 - Gly270 |
| Expression System | CHO |
| Activity | Active |
| Activity Note | Determinedd by the ability of the immobilized protein to support the adhesion of U937 human histiocytic lymphoma cells. The ED50 for this effect is less than 20 μg/mL. |
| Alternate Names | Membrane component chromosome 1 surface marker 1; M1S1; Cell surface glycoprotein Trop-2; TROP2; EGP-1; EGP1; Tumor-associated calcium signal transducer 2; GA733-1; Pancreatic carcinoma marker protein GA733-1; GA7331; GP50 |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | > 95% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | TACSTD2 |
|---|---|
| Gene Full Name | tumor-associated calcium signal transducer 2 |
| Background | This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009] |
| Function | May function as a growth factor receptor. [UniProt] |
| PTM | The N-terminus is blocked. [UniProt] |
