ARG82771

MPO / Myeloperoxidase Assay Kit (Fluorometric)

MPO / Myeloperoxidase Assay Kit (Fluorometric) for Functional study and All species,Human,Mouse,Rat

Overview

Product Description ARG82771 MPO / Myeloperoxidase Assay Kit (Fluorometric) is a detection kit for the quantification of Myeloperoxidase peroxidation in cell lysate and tissue.
Tested Reactivity Hu, Ms, Rat, All
Tested Application FuncSt
Target Name MPO / Myeloperoxidase
Conjugation Note λ ex/em = 530 / 585 nm (fluorometric)
Sensitivity 0.0025 U/L
Detection Range 0.0025 - 2 U/L
Sample Type Cell lysate and tissue.
Sample Volume 20 µl
Alternate Names MPO; Myeloperoxidase; EC 1.11.2.2

Application Instructions

Application Note Please note that this kit does not include a microplate.
Assay Time < 1 hour

Properties

Form Liquid
Storage Instruction Store the kit at -20°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 17523 Mouse MPO

GeneID: 4353 Human MPO

Swiss-port # P05164 Human Myeloperoxidase

Swiss-port # P11247 Mouse Myeloperoxidase

Gene Symbol MPO
Gene Full Name myeloperoxidase
Background Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]
Function Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. [UniProt]
Cellular Localization Lysosome. [UniProt]

Images (1) Click the Picture to Zoom In

  • ARG82771 MPO / Myeloperoxidase Assay Kit (Fluorometric) typical data demonstration image

    ARG82771 MPO / Myeloperoxidase Assay Kit (Fluorometric) results of a typical standard, using fluorometric reading.

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