ARG83760
Mouse CCL2 / MCP1 ELISA Kit
Mouse CCL2 / MCP1 ELISA Kit for ELISA and Mouse
Overview
| Product Description | ARG83760 Mouse CCL2 / MCP1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse CCL2 / MCP1 in serum, plasma and cell culture supernatants. |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | ELISA |
| Target Name | CCL2 / MCP1 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 1.95 pg/ml |
| Sample Type | Serum, plasma and cell culture supernatants. |
| Standard Range | 3.9 - 250 pg/ml |
| Sample Volume | 50 µl |
| Precision | Intra-Assay CV: <10% Inter-Assay CV: <10% |
| Alternate Names | CCL2; C-C Motif Chemokine Ligand 2; MCP-1; MCP1; MCAF; HC11; Monocyte Chemotactic And Activating Factor; Monocyte Secretory Protein JE; SMC-CF 2; GDCF-2; SCYA2; Small Inducible Cytokine A2 (Monocyte Chemotactic Protein 1, Homologous To Mouse Sig-Je); Small Inducible Cytokine Subfamily A (Cys-Cys), Member 2; Monocyte Chemoattractant Protein-1; Chemokine (C-C Motif) Ligand 2; Monocyte Chemotactic Protein 1; Small-Inducible Cytokine A2; C-C Motif Chemokine 2; MGC9434; Monocyte Chemotactic Protein 1, Homologous To Mouse Sig-Je; Monocyte Chemoattractant Protein 1; HSMCR30 |
Application Instructions
| Assay Time | 4 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 4°C, -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CCL2 |
| Gene Full Name | C-C Motif Chemokine Ligand 2 |
| Background | This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. [provided by RefSeq, Aug 2020] |
| Function | Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosi. [UniProt] |
| PTM | Disulfide bond, Glycoprotein, Pyrrolidone carboxylic acid. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG83760 Mouse CCL2 / MCP1 ELISA Kit standard curve image
ARG83760 Mouse CCL2 / MCP1 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG83760 Mouse CCL2 / MCP1 ELISA Kit User manual |
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