ARG83818
Mouse SOD2 ELISA Kit
Mouse SOD2 ELISA Kit for ELISA and Mouse
Overview
| Product Description | ARG83818 Mouse SOD2 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse SOD2 in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids |
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| Tested Reactivity | Ms |
| Tested Application | ELISA |
| Target Name | SOD2 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 15.625 pg/ml |
| Sample Type | Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids |
| Standard Range | 31.25-2000 pg/mL |
| Sample Volume | 100 μl |
| Precision | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| Alternate Names | MNSOD; Superoxide dismutase [Mn], mitochondrial; IPOB; EC 1.15.1.1; MVCD6 |
Application Instructions
| Assay Time | 3.5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P09671 Mouse Superoxide dismutase [Mn], mitochondrial |
|---|---|
| Gene Symbol | Sod2 |
| Gene Full Name | superoxide dismutase 2, mitochondrial |
| Background | This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| Function | Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. [UniProt] |
| Cellular Localization | Mitochondrion, Mitochondrion Matrix |
| PTM | Nitrated under oxidative stress. Nitration coupled with oxidation inhibits the catalytic activity. Acetylation at Lys-122 decreases enzymatic activity. Deacetylated by SIRT3 upon exposure to ionizing radiations or after long fasting (By similarity). |
Images (1) Click the Picture to Zoom In
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ARG83818 Mouse SOD2 ELISA Kit standard curve image
ARG83818 Mouse SOD2 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG83818 Mouse SOD2 ELISA Kit User manual |
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