Phospho JunB Antibody Duo (Total, pSer259)
Gene Regulation antibody
|Cat No||Component Name||Host clonality||Reactivity||Application||Package|
|ARG64936||anti-JunB antibody||Goat pAb||Hu||WB||50 μg|
|ARG51531||anti-JunB phospho (Ser259) antibody||Rabbit pAb||Hu, Ms, Rat||WB, IHC-P||50 μl|
|Product Description||JunB is a basic region, leucine zipper (bZIP) transcription factor belonging to the Jun family that includes c-Jun and JunD. Jun family members homodimerize or heterodimerize with Fos and ATF proteins to form a functional transcription factor AP-1 (activator protein 1), whose activity is regulated by a variety of physiological and pathological stimuli such as growth factors, infections, and stress signals. Phosphorylation of this residue enhances DNA binding of the JunB/AP-1 complex.
Busch, S.J. and Sassone-Corsi, P. (1990) Trends Genet. 6, 36-40.
Hess, J. et al. (2004) J. Cell Sci. 117, 5965-5973.
Mechta-Grigoriou, F. et al. (2001) Oncogene 20, 2378-2389.
Chiu, R. et al. (1989) Cell 59, 979-986.
JunB as a novel gate keeper for prostate cancer progression
|Alternate Names||Phospho JunB antibody; JunB phospho (Ser259) antibody; JunB antibody|
|Storage Instruction||For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.|
|Note||For laboratory research only, not for drug, diagnostic or other use.|
|Gene Full Name||Antibody Duo for Phospho JunB (Total, pSer259)|
|Research Area||Gene Regulation antibody|
Images (3) Click the Picture to Zoom In
ARG51531 anti-JunB phospho (Ser259) antibody WB image
Western Blot: extracts from HT29 cells untreated or treated with EGF stained with anti-JunB (phospho Ser259) antibody ARG51531.
ARG64936 anti-JUNB antibody WB image
Western Blot: Human Breast Cancer lysate (35 µg protein in RIPA buffer) stained with ARG64936 anti-JunB antibody at 0.3 µg/ml dilution.
ARG51531 anti-JunB phospho (Ser259) antibody IHC-P image
Immunohistochemistry: paraffin-embedded human breast carcinoma tissue stained with anti-JunB (phospho Ser259) antibody ARG51531 (left) or the same antibody preincubated with blocking peptide (right).