ARG70637
Puumala Virus Glycoprotein peptide
Puumala Virus Glycoprotein peptide for Blocking
Overview
| Product Description | The peptide is used for blocking the activity of anti-Puumala Virus Glycoprotein antibody ARG46773 |
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| Tested Application | BL |
| Target Name | Puumala Virus Glycoprotein |
| A.A. Sequence | 19 amino acids near the amino terminus of the Puumala virus glycoprotein. |
Application Instructions
| Application Suggestion |
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| Application Note | This peptide usually blocks anti-Puumala Virus Glycoprotein antibody ARG46773 activity completely by incubating the peptide with equal volume of antibody for 30 min at at 37°C. |
Properties
| Form | Liquid |
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| Buffer | PBS (pH 7.2), 0.02% sodium azide and 0.1% BSA |
| Concentration | 200 µg/ml |
| Storage Instruction | Store peptide at -20°C, stable for one year. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Background | Puumala virus (PUUV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) and is highly homologous to the protype hantavirus Hantaan virus (1). Like other hantaviruses, the PUUV glycoprotein is synthesized as a precursor that is posttranslationally processed into two glycoproteins G1 (Gn) and G2 (Gc). These glycoproteins interact with the PUUV nucleocapsid (NP) protein through their cytoplasmic tail, and this association has been suggested to be crucial to the binding of the ribonucleoprotein of the PUUV and the assembly of the virus particle (2). |
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