ARG30274

SOD1 and SOD2 Antibody Duo

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Component

Cat No Component Name Host clonality Reactivity Application Package
ARG64241 anti-SOD1 antibody Goat pAb Hu, Ms ICC/IF, WB 50 μg
ARG54937 anti-SOD2 antibody Rabbit pAb Hu, Ms, Rat ICC/IF, IHC-P, IHC-Fr, WB 50 μl

Overview

Product Description

Superoxide Dismutases (SODs, including SOD1 and SOD2) are enzymes that alternately catalyzes the dismutation of superoxide radicals into less damaging molecular oxygen or hydrogen peroxide. The overproduction of superoxide radicals can cause severe tissue and cell damages. SOD enzymes deal with the superoxide radical by alternately adding or removing an electron from the superoxide molecules it encounters, thus changing the O2− into one of two less damaging species: either molecular oxygen (O2) or hydrogen peroxide (H2O2). SOD1 and SOD2 became the most important antioxidant defense systems in almost all living things exposed to oxygen.

Fukui and Bao. 2010. Free Rad Biol and Med 6: 821-830
Nojima et al. 2015. Plos One 25(10)

Target Name SOD1 and SOD2
Alternate Names SOD1 and SOD2 antibody; Superoxide dismutase 1 and Superoxide dismutase 2 antibody; SOD2 antibody; SOD1 antibody

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Images (11) Click the Picture to Zoom In

  • ARG64241 anti-SOD1 antibody WB image

    Western blot: 30 µg of HeLa cell lysate stained with ARG64241 anti-SOD1 antibody at 1:2000 dilution.

  • ARG54937 anti-SOD2 antibody ICC/IF image

    Immunofluorescence: 100% Methanol fixed (RT, 10 min) HeLa cells stained with ARG54937 anti-SOD2 antibody (orange) at 1:10 dilution.

    Secondary antibody: ARG21917 Goat anti-Rabbit IgG antibody (TRITC)

  • ARG54937 anti-SOD2 antibody WB image

    Western blot: 30 µg of HeLa, HepG2, MDAMB231, HEK293T, Mouse heart, Mouse liver, and Rat heart lysates stained with ARG54937 anti-SOD2 antibody at 1:500 dilution.

  • ARG64241 anti-SOD1 antibody WB image

    Western blot: 30 µg of HeLa cell lysate stained with ARG64241 anti-SOD1 antibody at 1:2000 dilution.

  • ARG64241 anti-SOD1 antibody ICC/IF image

    Immunofluorescence: Paraformaldehyde-fixed U2OS cells, permeabilized with 0.15% Triton. Cells were stained with ARG64241 anti-SOD1 antibody (green) at 10 µg/ml dilution for 1 hour. DAPI (blue) for nuclear staining. Negative control: Unimmunized Goat IgG (green) at 10 µg/ml dilution.

  • ARG54937 anti-SOD2 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human oophoroma stained with ARG54937 anti-SOD2 antibody at 1:100 dilution (400x lens).

  • ARG54937 anti-SOD2 antibody IHC-P image

    Immunohistochemistry: paraffin-embedded Rat heart stained with ARG54937 anti-SOD2 antibody at 1:100 dilution (400x lens).

  • ARG64241 anti-SOD1 antibody WB image

    Western blot: 30 µg of Mouse brain lysate stained with ARG64241 anti-SOD1 antibody at 1:2000 dilution.

  • ARG64241 anti-SOD1 antibody WB image

    Western blot: 30 µg of Mouse brain lysate stained with ARG64241 anti-SOD1 antibody at 1:2000 dilution.

  • ARG64241 anti-SOD1 antibody ICC/IF image

    Immunofluorescence: Paraformaldehyde-fixed A431 cells, permeabilized with 0.15% Triton. Cells were stained with ARG64241 anti-SOD1 antibody (green) at 10 µg/ml dilution for 1 hour. DAPI (blue) for nuclear staining. Negative control: Unimmunized Goat IgG (green) at 10 µg/ml dilution.

  • ARG54937 anti-SOD2 antibody IHC-P image

    Immunohistochemistry: paraffin-embedded Human oophoroma stained with ARG54937 anti-SOD2 antibody at 1:100 dilution (400x lens).

Specific References

Dietary Fe 3 O 4 Nanozymes Prevent the Injury of Neurons and Blood-Brain Barrier Integrity from Cerebral Ischemic Stroke.

ARG54937: WB / Mouse

Bing Chun Yan et al.
ACS Biomater Sci Eng.,  (2021)

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The antiepileptic drug levetiracetam promotes neuroblast differentiation and expression of superoxide dismutase in the mouse hippocampal dentate gyrus via PI3K/Akt signalling.

ARG54937: WB / Mouse

Yan Bing-Chun et al.
Neurosci Lett.,  (2018)

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Topiramate Improves Neuroblast Differentiation of Hippocampal Dentate Gyrus in the D-Galactose-Induced Aging Mice via Its Antioxidant Effects.

ARG54937: WB/IHC-F / Mouse

Shen H et al.
Cell Mol Neurobiol.,  (2016)

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