ARG45970

anti-AAK1 antibody

anti-AAK1 antibody for Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes AAK1
Tested Reactivity Hu, Ms, Rat
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name AAK1
Antigen Species Human
Immunogen A 20 amino acid synthetic peptide within aa. 190 - 240 of human AAK1.
Conjugation Un-conjugated
Alternate Names AAK1; AP2-associated protein kinase 1; EC 2.7.11.1; Adaptor-associated kinase 1

Application Instructions

Application Suggestion
Tested Application Dilution
WBAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Purification Affinity chromatography purified
Buffer PBS and 0.02% Sodium azide.
Preservative 0.02% Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 22848 Human AAK1

GeneID: 269774 Mouse AAK1

Swiss-port # Q2M2I8 Human AP2-associated protein kinase 1

Swiss-port # Q3UHJ0 Mouse AP2-associated protein kinase 1

Gene Symbol AAK1
Gene Full Name AP2 associated kinase 1
Background Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Calculated MW 104 kDa
PTM Autophosphorylated.

Images (1) Click the Picture to Zoom In

  • ARG45970 anti-AAK1 antibody WB image

    Western blot: A-20 stained with ARG45970 anti-AAK1 antibody.