ARG45686
anti-ABCB6 / PRP antibody
anti-ABCB6 / PRP antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ABCB6 / PRP |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ABCB6 / PRP |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to C-terminal region of human ABCB6 / PRP. |
| Conjugation | Un-conjugated |
| Alternate Names | ABCB6; ATP Binding Cassette Subfamily B Member 6 (LAN Blood Group); MTABC3; Umat; ATP Binding Cassette Subfamily B Member 6 (Langereis Blood Group); Ubiquitously-Expressed Mammalian ABC Half Transporter; ATP-Binding Cassette Sub-Family B Member 6; ATP-Binding Cassette Half-Transporter; ABC-Type Heme Transporter ABCB6; Mitochondrial ABC Transporter 3; P-Glycoprotein-Related Protein; Mt-ABC Transporter 3; EST45597; PRP; ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (Langereis Blood Group); ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6; EC 7.6.2.5; EC 3.6.3 47; UMAT; ABC; LAN |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 94 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Thimerosal and 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9NP58 Human ATP-binding cassette sub-family B member 6, mitochondrial |
|---|---|
| Gene Symbol | ABCB6 |
| Gene Full Name | ATP Binding Cassette Subfamily B Member 6 (LAN Blood Group) |
| Background | This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. This protein is a member of the heavy metal importer subfamily and plays a role in porphyrin transport. This gene is the molecular basis of the Langereis (Lan) blood group antigen and mutations in this gene underlie familial pseudohyperkalemia and dyschromatosis universalis hereditaria. [provided by RefSeq, Mar 2017] |
| Function | ATP-dependent transporter that catalyzes the transport of a broad-spectrum of porphyrins from the cytoplasm to the extracellular space through the plasma membrane or into the vesicle lumen. [UniProt] |
| Cellular Localization | Cell membrane; Endoplasmic reticulum; Endosome; Golgi apparatus; Lysosome; Membrane; Mitochondrion; Mitochondrion outer membrane; Secreted. [UniProt] |
| Calculated MW | 94 kDa |
| PTM | Disulfide bond; Glycoprotein. [UniProt] |
Images (2) Click the Picture to Zoom In
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ARG45686 anti-ABCB6 / PRP antibody IHC-P image
Immunohistochemistry: Human mammary cancer stained with ARG45686 anti-ABCB6 / PRP antibody.
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ARG45686 anti-ABCB6 / PRP antibody WB image
Western blot: Hela stained with ARG45686 anti-ABCB6 / PRP antibody at 0.5 μg/ml dilution.
