ARG45442
anti-ABP1 antibody
anti-ABP1 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Monkey
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ABP1 |
|---|---|
| Tested Reactivity | Hu, Mk |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ABP1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human ABP1. |
| Conjugation | Un-conjugated |
| Alternate Names | AOC1; Amine oxidase copper domain-containing protein 1; Amiloride-binding protein 1; Histaminase; KAO; DAO; ABP1; DAO1; Amiloride-sensitive amine oxidase [copper-containing]; ABP; Kidney amine oxidase; Diamine oxidase; EC 1.4.3.22 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 90 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P19801 Human Amiloride-sensitive amine oxidase [copper-containing] |
|---|---|
| Gene Symbol | AOC1 |
| Gene Full Name | amine oxidase, copper containing 1 |
| Background | This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013] |
| Function | Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function. [UniProt] |
| Cellular Localization | Cell membrane. [UniProt] |
| Calculated MW | 85 kDa |
| PTM | Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. [UniProt] |
Images (5) Click the Picture to Zoom In
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ARG45442 anti-ABP1 antibody IHC-P image
Immunohistochemistry: Human colorectal adenocarcinoma stained with ARG45442 anti-ABP1 antibody at 2 μg/ml dilution.
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ARG45442 anti-ABP1 antibody ICC/IF image
Immunofluorescence: T-47D stained with ARG45442 anti-ABP1 antibody at 5 μg/ml dilution.
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ARG45442 anti-ABP1 antibody WB image
Western blot: 293T stained with ARG45442 anti-ABP1 antibody at 0.5 μg/ml dilution.
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ARG45442 anti-ABP1 antibody FACS image
Flow Cytometry: THP-1 stained with ARG45442 anti-ABP1 antibody at 1 µg/10^6 cells dilution.
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ARG45442 anti-ABP1 antibody WB image
Western blot: COS-7 stained with ARG45442 anti-ABP1 antibody at 0.5 μg/ml dilution.
