ARG46839
anti-ACAD8 antibody
anti-ACAD8 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes ACAD8 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | ACAD8 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human ACAD8. |
| Conjugation | Un-conjugated |
| Alternate Names | ACAD8; Isobutyryl-CoA dehydrogenase; mitochondrial; ARC42; IBD; Activator-recruited cofactor 42 kDa component; Acyl-CoA dehydrogenase family member 8; ACAD-8 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Buffer | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9UKU7 Human Isobutyryl-CoA dehydrogenase, mitochondrial |
|---|---|
| Gene Symbol | ACAD8 |
| Gene Full Name | Isobutyryl-CoA dehydrogenase, mitochondrial |
| Background | This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. The encoded protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid valine. Defects in this gene are the cause of isobutyryl-CoA dehydrogenase deficiency.[provided by RefSeq, Nov 2009] |
| Function | Isobutyryl-CoA dehydrogenase which catalyzes the conversion of 2-methylpropanoyl-CoA to (2E)-2-methylpropenoyl-CoA in the valine catabolic pathway. [UniProt] |
| Cellular Localization | Mitochondrion. [UniProt] |
| Calculated MW | 45 kDa |
| PTM | Acetylation. [UniProt] |
