anti-ACE2 antibody

anti-ACE2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human


Product Description

Rabbit Polyclonal antibody recognizes ACE2

Tested Reactivity Hu
Predict Reactivity Ms
Tested Application ICC/IF, IHC-P, WB
Specificity This antibody has no cross response to ACE1.
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name ACE2
Antigen Species Human
Immunogen Synthetic peptide within aa. 180-230 of Human ACE2.
Conjugation Un-conjugated
Alternate Names Angiotensin-converting enzyme homolog; ACEH; Angiotensin-converting enzyme 2; Metalloprotease MPROT15; ACE-related carboxypeptidase; EC

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF20 µg/ml
IHC-P2 µg/ml
WB2 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Human Kidney Tissue Lysate
Observed Size ~ 105 kDa


Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS and 0.02% Sodium azide
Preservative 0.02% Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 59272 Human ACE2

Swiss-port # Q9BYF1 Human Angiotensin-converting enzyme 2

Gene Symbol ACE2
Gene Full Name angiotensin I converting enzyme 2
Background The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq, Jul 2008]
Function Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses. [UniProt]
Highlight Related products:
ACE2 antibodies; ACE2 ELISA Kits; ACE2 recombinant proteins; Anti-Rabbit IgG secondary antibodies;
Related news:
HMGB1, a biomarker and therapeutic target in COVID-19
ACE2, receptor of 2019-nCoV
Calculated MW 92 kDa
PTM N-glycosylation on Asn-90 may limit SARS infectivity.
Proteolytic cleavage by ADAM17 generates a secreted form. Also cleaved by serine proteases: TMPRSS2, TMPRSS11D and HPN/TMPRSS1.

Images (3) Click the Picture to Zoom In

  • ARG55800 anti-ACE2 antibody WB image

    Western blot: Human kidney lysate stained with ARG55800 anti-ACE2 antibody at (A) 0.5, (B) 1, and (C) 2 µg/ml dilution.

  • ARG55800 anti-ACE2 antibody IHC-P image

    Immunohistochemistry: paraffin-embedded Human kidney tissue stained with ARG55800 anti-ACE2 antibody at 2 µg/ml dilution.

  • ARG55800 anti-ACE2 antibody ICC/IF image

    Immunofluorescence: Human Kidney cells stained with ARG55800 anti-ACE2 antibody at 20 µg/ml dilution.