Overview

Product Description	Rabbit Polyclonal antibody recognizes ACSL1
Tested Reactivity	Hu, Ms, Rat
Tested Application	WB
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Target Name	ACSL1
Antigen Species	Human
Immunogen	A 18 amino acid synthetic peptide within aa. 240 - 290 of human ACSL1.
Conjugation	Un-conjugated
Alternate Names	ACSL1; LACS 2; Long-chain acyl-CoA synthetase 2; LACS1; ACS1; LACS2; Long-chain-fatty-acid--CoA ligase 1; Long-chain acyl-CoA synthetase 1; FACL2; FACL1; LACS; EC 6.2.1.3; LACS 1; Long-chain fatty acid-CoA ligase 2; Acyl-CoA synthetase 1; Palmitoyl-CoA ligase 1; Palmitoyl-CoA ligase 2

Application Instructions

Application Suggestion	Tested Application Dilution WB Assay-dependent
Application Note	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size	45,47 kDa

Properties

Purification	Affinity chromatography purified
Buffer	PBS and 0.02% Sodium azide.
Preservative	0.02% Sodium azide
Concentration	1 mg/ml
Storage Instruction	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links	GeneID: 14081 Mouse ACSL1 GeneID: 2180 Human ACSL1 GeneID: 25288 Rat ACSL1 Swiss-port # P18163 Rat Long-chain-fatty-acid--CoA ligase 1 Swiss-port # P33121 Human Long-chain-fatty-acid--CoA ligase 1 Swiss-port # P41216 Mouse Long-chain-fatty-acid--CoA ligase 1 More
Gene Symbol	ACSL1
Gene Full Name	acyl-CoA synthetase long-chain family member 1
Background	The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Function	Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate. [UniProt]
Calculated MW	41,58,77 kDa

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