ARG10771

anti-ADCY5 antibody

anti-ADCY5 antibody for Confocal microscopy (Confocal),ELISA,ICC/IF,Immunohistochemistry,Immunoprecipitation,Western blot,Dot blot and Human,Rat,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes ADCY5
Tested Reactivity Hu, Ms, Rat
Tested Application Confocal, Dot, ELISA, ICC/IF, IHC, IP, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name ADCY5
Antigen Species Rat
Immunogen Synthetic peptide from Rat ADCY5.
Conjugation Un-conjugated
Full Name adenylate cyclase 5
Alternate Names FDFM; ATP pyrophosphate-lyase 5; AC5; Adenylate cyclase type V; Adenylate cyclase type 5; EC 4.6.1.1; Adenylyl cyclase 5

Application Instructions

Application Suggestion
Tested Application Dilution
Confocal1:200 - 1:1000
Dot1:10000
ELISA1:10000
ICC/IF1:200 - 1:1000
IHC1:200 - 1:1000
IP1:200
WB1:500
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Calculated MW 139 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 30% Glycerol and 0.5% BSA
Concentration 0.5 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 111 Human ADCY5

GeneID: 224129 Mouse ADCY5

GeneID: 64532 Rat ADCY5

Gene Symbol Adcy5
Gene Full Name adenylate cyclase 5
Background This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Function This is a membrane-bound, calcium-inhibitable adenylyl cyclase. [UniProt]
PTM Phosphorylated by RAF1.

Images (2) Click the Picture to Zoom In

  • ARG10771 anti-ADCY5 antibody ICC/IF image

    Immunofluorescence: Rat striatal neurons stained with ARG10771 anti-ADCY5 antibody.

  • ARG10771 anti-ADCY5 antibody WB image

    Western blot: Recombinant ADCY5 protein stained with ARG10771 anti-ADCY5 antibody at 1:500 dilution.