ARG45479
anti-AGPS antibody
anti-AGPS antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes AGPS |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | AGPS |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human AGPS. |
| Conjugation | Un-conjugated |
| Alternate Names | ADHAPS; ALDHPSY; EC 2.5.1.26; ADAS; ADAP-S; Alkyldihydroxyacetonephosphate synthase, peroxisomal; Alkyl-DHAP synthase; Alkylglycerone-phosphate synthase; ADPS; Aging-associated gene 5 protein |
Application Instructions
| Application Suggestion |
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 73 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O00116 Human Alkyldihydroxyacetonephosphate synthase, peroxisomal |
|---|---|
| Gene Symbol | AGPS |
| Gene Full Name | alkylglycerone phosphate synthase |
| Background | AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse. |
| Function | Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. [UniProt] |
| Cellular Localization | Membrane; Peroxisome. [UniProt] |
| Calculated MW | 73 kDa |
| PTM | Acetylation; Phosphoprotein. [UniProt] |
Images (4) Click the Picture to Zoom In
-
ARG45479 anti-AGPS antibody IHC-P image
Immunohistochemistry: Human adenocarcinoma of lung stained with ARG45479 anti-AGPS antibody at 2 μg/ml dilution.
-
ARG45479 anti-AGPS antibody ICC/IF image
Immunofluorescence: SiHa stained with ARG45479 anti-AGPS antibody at 5 μg/ml dilution.
-
ARG45479 anti-AGPS antibody WB image
Western blot: Hela stained with ARG45479 anti-AGPS antibody at 0.5 μg/ml dilution.
-
ARG45479 anti-AGPS antibody FACS image
Flow Cytometry: U937 stained with ARG45479 anti-AGPS antibody at 1 µg/10^6 cells dilution.
