anti-AGR2 + AGR3 antibody [AGR3.4]

anti-AGR2 + AGR3 antibody [AGR3.4] for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Cancer antibody; Signaling Transduction antibody


Product Description

Mouse Monoclonal antibody [AGR3.4] recognizes AGR2 + AGR3

Tested Reactivity Hu
Tested Application ICC/IF, IHC-P, WB
Specificity The clone AGR3.4 recognizes the PLMII epitope of AGR3 (AG3) and AGR2 (AG2) proteins (19-20 kDa); secreted cytoplasmic proteins which can serve as markers of carcinogenesis.
Host Mouse
Clonality Monoclonal
Clone AGR3.4
Isotype IgG1
Target Name AGR2 + AGR3
Antigen Species Human
Immunogen Purified human AGR3 protein
Conjugation Un-conjugated
Alternate Names Anterior gradient protein 2 homolog; Secreted cement gland protein XAG-2 homolog; hAG-2; GOB-4; HAG-2; HPC8; PDIA17; HEL-S-116; AG-2; XAG-2; AG2

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1 µg/ml
IHC-P5 µg/ml
WB1 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control WB and ICC/IF: Positive control: T47D. Negative control: H1299
IHC-P: Positive control: Human colon


Form Liquid
Purification Purified from ascites by protein-A affinity chromatography.
Purity > 95% (by SDS-PAGE)
Buffer PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
Preservative 15 mM Sodium azide
Stabilizer 0.2% (w/v) high-grade protease free BSA
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 10551 Human AGR2

Swiss-port # O95994 Human Anterior gradient protein 2 homolog

Gene Symbol AGR2
Gene Full Name anterior gradient 2
Background AGR2 (Anterior Gradient 2), also known as AG2 (hAG-2, HAG2 in human), or GOB-4, and AGR3 (Anterior Gradient 3), also known as AG3 (hAG-3, HAG3 in human), or BCMP11, are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours; AGR2 was reported also as a marker of other carcinomas. Xenopus homolog of these proteins is associated with anteroposterior fate determination during early development.
Function Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. [UniProt]
Research Area Cancer antibody; Signaling Transduction antibody
Calculated MW 20 kDa

Images (2) Click the Picture to Zoom In

  • ARG53742 anti-AGR2 + AGR3 antibody [AGR3.4] WB image

    Western blot: 1) H1229 cell lysate, and 2) T47D cell lysate stained with ARG53742 anti-AGR2 + AGR3 antibody [AGR3.4].

  • ARG53742 anti-AGR2 + AGR3 antibody [AGR3.4] IHC-P image

    Immunohistochemistry: Human colon (paraffin sections) stained with ARG53742 anti-AGR2 + AGR3 antibody [AGR3.4].