ARG45980
anti-AID antibody
anti-AID antibody for Western blot,ICC/IF and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes AID |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | AID |
| Antigen Species | Human |
| Immunogen | A 14 amino acid synthetic peptide within the last 50 amino acids of human AID. |
| Conjugation | Un-conjugated |
| Alternate Names | AICDA; Cytidine aminohydrolase; CDA2; HIGM2; Activation-induced cytidine deaminase; AID; EC 3.5.4.38; ARP2; Single-stranded DNA cytosine deaminase; HEL-S-284 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 25 kDa |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9GZX7 Human Single-stranded DNA cytosine deaminase Swiss-port # Q9WVE0 Mouse Single-stranded DNA cytosine deaminase |
|---|---|
| Gene Symbol | AICDA |
| Gene Full Name | activation-induced cytidine deaminase |
| Background | This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Feb 2009] |
| Calculated MW | 22 kDa |
| PTM | Ser-38 is the major site whereas Thr-27 is the minor site of phosphorylation. Phosphorylation regulates its class-switch recombination activity. Probably monoubiquitinated on several residues by RNF126. |
Images (2) Click the Picture to Zoom In
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ARG45980 anti-AID antibody ICC/IF image
Immunofluorescence: Ramos stained with ARG45980 anti-AID antibody.
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ARG45980 anti-AID antibody WB image
Western blot: Ramos stained with ARG45980 anti-AID antibody.
